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Updated: Feb 16, 2026

Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test
06:59

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Published on: November 13, 2016

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FBXW7変異は,ETV6-GLUT1軸を活性化することで,グルコース代謝を再プログラムする

Siqi Fei1,2,3, Xiayun Xu2, Tingrui Wang2

  • 1Department of Clinical Laboratory, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, 200092, P.R. China.

Molecular cancer
|February 14, 2026
PubMed
まとめ

FBXW7の変異は,ETV6を安定させ,グルコーストランスポーター1 (GLUT1) の発現を増加させることで,子宮内膜がん (EC) のグルコース代謝を乱します. これは腫瘍の成長を促しますが,GLUT1を標的とした治療は,FBXW7変異のECに対する潜在的な治療法を提供します.

キーワード:
子宮内膜がんは子宮内膜がんである.FBXW7はFBXW7に該当する.グルコースの代謝ユビキチネーション (Ubiquitination) とは ユビキチネーション (Ubiquitination) とは ユビキチネーション (Ubiquitination) とは

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