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Updated: Feb 16, 2026

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FUSとDNAのナノスケールの共圧縮と伸縮抵抗

Weiqian Dong1, Wen-Ting Chu2, Erkang Wang1

  • 1State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China; University of Science and Technology of China, Hefei 230029, China.

Biophysical journal
|February 15, 2026
PubMed
まとめ

機械的なストレスは,遺伝子調節に不可欠なタンパク質-DNA共コンデンサに影響を及ぼします. シミュレーションでは,FUSとDNAが異なる形で貢献し,ストレッチ下での遅延反応と構造変化を示し,生物学的プロセスへの洞察を提供している.

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