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Updated: Feb 16, 2026

Live Imaging to Study Microtubule Dynamic Instability in Taxane-resistant Breast Cancers
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格子不安定性は,マイクロチューブルプラスエンドチップのプロトフィラメントクラスターの形成を促します

Weizhi Xue1, Jiangbo Wu1, Tamara Bidone2

  • 1Department of Chemistry, Chicago Center for Theoretical Chemistry, The James Franck Institute, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, Illinois 60637, United States.

Biophysical journal
|February 15, 2026
PubMed
まとめ

マイクロチューブル (MTs) は,そのダイナミックなプラスエンドの先端にプロトフィラメント (PF) クラスターを示します. これらのクラスターは,格子不安定によって駆動され,MTダイナミクスと災害に影響を与え,チューブリンの構成的変動性に関する洞察を提供します.

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