関連する実験動画

Updated: Feb 16, 2026

Dual Bioluminescence Imaging of Tumor Progression and Angiogenesis
10:56

Dual Bioluminescence Imaging of Tumor Progression and Angiogenesis

Published on: August 1, 2019

8.8K

腫瘍血管新生のための治療戦略として,先端内皮細胞の選択的標的化

Byoungmo Kim1, Ha Kyeong Lee1, Zulfikar Azam2

  • 1College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|February 15, 2026
PubMed
まとめ

私たちは,ドッペルを,新しい血管の成長に不可欠な,内皮の尖端細胞 (TipECs) のターゲッタブルレギュレータとして特定しました. ドッペルを抗体で標的にすることで,TipECsを特異的に枯渇させることで,腫瘍の成長を効果的に減少させ,新しい抗血管新生療法戦略を提供しました.

キーワード:
アンジオゲネシス アンジオゲネシスモノクローナル抗体である.尖端細胞は,先端細胞である.腫瘍療法とは,腫瘍治療である.

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