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Updated: Feb 16, 2026

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
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HR陽性/HER2陰性乳がんにおけるダトポタマブ・デルクステカンの最適な用量の正当化は,モデルの情報に基づく薬物開発アプローチを通じて行われます

Zoey Tang1, KyoungSoo Lim1, Yu Jiang1

  • 1Clinical Pharmacology and Quantitative Pharmacology, AstraZeneca, Gaithersburg, Maryland, USA.

Clinical and translational science
|February 15, 2026
PubMed
まとめ

モデルに基づく薬物開発は,HR+/HER2-乳がんの治療に3週間ごとに6mg/kgのダトポタマブ・デルクステカン (Dato-DXd) の投与量を検証し,腫瘍制御の改善と無進行生存率を示した.

キーワード:
ADCのADCは,ADCのADCとして,ADCはADCとして,ADCはADCとして,ADCはADCとして.日時‐DXddでした.HR+/HER2− 乳がんについてトロップ2 (TROP2) とは

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