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Updated: Feb 17, 2026

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転写因子E4BP4の欠乏は,血管損傷後のネオインティマルの形成を抑制する

Fumie Ohtomo1, Kikuo Isoda2, Tomiharu Niida3

  • 1Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo, Japan.

Atherosclerosis
|February 15, 2026
PubMed
まとめ

E4BP4欠乏症は,血管損傷後のマウスのネオインティマル形成と炎症性サイトカインを著しく減少させた. これは,E4BP4の抑制が,高山大動脈炎 (TAK) を含む血管炎の治療戦略である可能性があることを示唆しています.

キーワード:
サイトカインはサイトカインをE4結合タンパク質4 4炎症 炎症 炎症 炎症 炎症ネオインティミアとは,ネオインティミアです.

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