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Updated: Feb 17, 2026

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes
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乳がん放射線治療のゲノムパーソナライゼーションに向けて: 基礎,課題,臨床統合のためのロードマップ

Pierre Loap1, Irene Buvat2, Gilles Crehange1

  • 1Department of Radiation Oncology, Institut Curie, Paris, France; Advanced Therapy in Radiation Oncology and Molecular Imaging Characterisation (ATOMIC), Institut Curie, Orsay, France; Proton Therapy Center (CPO), Institut Curie, Orsay, France.

Breast (Edinburgh, Scotland)
|February 15, 2026
PubMed
まとめ

放射線感受性指数 (RSI) やゲノム調整放射線量 (GARD) などのトランスクリプトームバイオマーカーを使用して,乳がん放射線治療用量を個別化することで,治療を調整することができます. これらのツールは,投与量のエスカレーションまたはデエスカレーションのために患者のサブグループを特定し,アウトカムを改善します.

キーワード:
乳がん 乳がんは乳がんです.ゲノム調整放射線量 (GARD) とはパーソナライズされた放射線療法ラジオゲノミクス (Radiogenomics) とは放射性感受性指数 (RSI) とは,放射性感受性指数 (RSI) とは,放射性感受性指数 (RSI) とは,放射性感受性の指数 (RSI) とは,放射性感受性の指数 (RSI) とは,放射性感受性の指数 (RSI) とは,放射性感受性の指数 (RSI) とは,放射性感受性の指数 (RSI) とは,放射性感受性の指数 (RSI) とは,放射性感受性の指数 (RSI) とは,放射性感受性の指数 (RSI) とは,放射性感受性の指数 (RSI) とは,放射性感受性の指数 (RSI) とは.

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