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Updated: Feb 17, 2026

Native Polyacrylamide Gel Electrophoresis Immunoblot Analysis of Endogenous IRF5 Dimerization
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Native Polyacrylamide Gel Electrophoresis Immunoblot Analysis of Endogenous IRF5 Dimerization

Published on: October 6, 2019

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ストレスを依存する直接結合による界面競争は,IgG4の安定化を強化する

Yan Gao1, Hengqian Wu2, Lili Wang2

  • 1School of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250000, China.

International journal of biological macromolecules
|February 15, 2026
PubMed
まとめ

この研究は,ポリソルベートとポロキサマー188が,異なるストレス下において,免疫グロブリンG4 (IgG4) モノクローナル抗体 (mAbs) を安定させる方法を明らかにしています. 薬の有効性は,ストレスタイプと表面活性物質の濃度と,臨界ミセル濃度 (CMC) に相対的に依存しています.

キーワード:
アグリゲーション アグリゲーション臨界ミセル濃度 (CMC) とはIgG4 IgG4 についてポーロキサマー 188ポリソルバテはポリソルバテからなる.

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