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Updated: Feb 17, 2026

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大腸を標的とした微生物群を調節するナノ粒子は,炎症性腸疾患における腸微生物群軸の再構築を通じてアザチオプリンの有効性を増幅します

Jingjing Zhang1, Yanni Zhang2, Xiao Lu1

  • 1Clinical Research Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.

Journal of nanobiotechnology
|February 15, 2026
PubMed
まとめ

この研究では,炎症性腸疾患 (IBD) の治療のために,アザチオプロイン (AZA) を搭載した新しいナノ粒子 (APZE) が開発されました. APZEは結腸にAZAを効果的に投与し,IBDモデルの炎症を軽減し,腸の健康を改善しました.

キーワード:
アザチオプリン (azathioprine) とは大腸をターゲットにした.腸内微生物群 (gut microbiota) は,腸内微生物群 (gut microbiota) と呼ばれている.炎症性腸疾患は,炎症性腸疾患で,炎症性腸疾患は炎症性腸疾患で,炎症性腸疾患は炎症性腸疾患で,炎症性腸疾患は炎症性腸疾患で,炎症性腸疾患は炎症性腸疾患で,炎症性腸疾患は炎症性腸疾患で,炎症性腸疾患は炎症性腸疾患で,炎症性腸疾患は炎症性腸疾患で.オーラル・デリバリー オーラル・デリバリー

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