SUNプロジェクトにおける地中海食と成人発症喘息の発生との関連:スペインの将来性コホート研究
Javier Errasti Viader1,2, Carmen de la Fuente-Arrillaga1,3,4, Arantza Campo Ezquibela5
1Department of Preventive Medicine and Public Health, University of Navarra-IDISNA, Pamplona, Spain.
まとめ
地中海ダイエット (MedDiet) を遵守すると,喘息のリスクが低下する可能性があります. この研究では,MedDietの遵守率が高い成人は,新たに発症した喘息の発生率が著しく低下したことが判明しました. キーワード:地中海ダイエット,喘息,発生率,成人.
科学分野:
- 栄養科学 栄養学 栄養科学は,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学は,栄養学が,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は
- エピデミオロジー エピデミオロジー
- 呼吸器医学とは
背景:
- ダイエット要因は喘息の発症に関与しているが,証拠は定かではない.
- 地中海ダイエット (MedDiet) は,さまざまな健康上の利点と関連している食事パターンです.
- 成人の発症性喘息におけるMedDietの役割を調査することは極めて重要です.
研究 の 目的:
- 地中海ダイエット (MedDiet) の遵守と成人発喘息の発生率との関連を調べる.
- 潜在的に変更可能な喘息の危険因子としての食事パターンを調査する.
主な方法:
- 食習慣と喘息診断を含むSUNコホート研究 (Seguimiento Universidad de Navarra) のデータを活用した.
- 定義された大人の発症性喘息は,ベースラインで呼吸道疾患のない成人の自己報告診断である.
- 食事頻度アンケートを使用して食事習慣を評価し,遵守のために地中海ダイエットスコア (MDS) を計算しました.
- MDSと喘息の発生率の関連性を分析するために,多変数繰り返し測定のコックスモデルを使用した.
主要な成果:
- 17,127人のコホートは平均12.8年間追跡され,302人 (1.76%) が新発性喘息を発症しました.
- MedDietの遵守率が高いことは,新たに診断された喘息のリスクの低下と有意に関連していました.
- 最も高いアデランスグループ (MDS ≥ 7) の個人は,最も低いアデランスグループ (MDS ≤ 2) に比べて,喘息のリスクが42%低かった (HR: 0.58; 95% CI: 0.36-0.95; p-trend=0.02).
結論:
- この研究は,地中海食のより高い遵守と成人における喘息の発生率の低下との間の有意な関連性を示す証拠を提供します.
- 地中海人口における大人の発症性喘息に対する保護的な食事因子としてのMedDietの潜在的な役割を強調する.
- MedDietを強調する食事介入が,喘息予防の戦略である可能性があることを示唆しています.
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