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Updated: Feb 17, 2026

Protection of H9c2 Myocardial Cells from Oxidative Stress by Crocetin via PINK1/Parkin Pathway-Mediated Mitophagy
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Protection of H9c2 Myocardial Cells from Oxidative Stress by Crocetin via PINK1/Parkin Pathway-Mediated Mitophagy

Published on: May 26, 2023

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CREG1は,PINK1/パーキン媒介型ミトファギーの経路を通じたコンドロサイト熱滅亡を抑制することで,骨格関節炎の進行を緩和する

Xianming Fei1, Shuanggong Liu2, Guangxu Song2

  • 1Department of Orthopaedics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.

Biotechnology journal
|February 16, 2026
PubMed
まとめ

E1A刺激遺伝子1 (CREG1) の細胞抑制剤は,コンドロサイト炎症を減少させることで,骨格関節炎 (OA) に対して保護します. CREG1はミトファジーとミトコンドリア機能を強化し,OAの潜在的な治療標的となる.

キーワード:
CREG1は,CREG1に準拠しています.NLRP3炎症ゾームであるミトファジー (mitophagy) とは,ミトファギーのことです.骨格関節炎 (Osteoarthritis) とは,骨格関節炎 (Osteoarthritis) とは,骨格関節炎 (Osteoarthritis) とは,骨格関節炎 (Osteoarthritis) とは,骨格関節炎 (Osteoarthritis) とは,ピロプトーシスである.

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