抗生物質補助剤の臨床前薬動力学と薬動力学

Viet Tin Pham1, David M P De Oliveira2, Andy Kuo1

  • 1Centre for Integrated Preclinical Drug Development, School of Biomedical Sciences, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, St Lucia Campus, Brisbane, QLD 4072, Australia.

ACS infectious diseases
|February 16, 2026
PubMed
まとめ

抗菌剤耐性 (AMR) は新しい戦略を要求しています. 既存の薬剤と併用された抗生物質補助剤は有望な結果を示していますが,それらの薬理動力学/薬理動力学 (PK/PD) 関係は,従来のMICベースのアプローチを超えた新しい分析方法を必要とします.

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