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Updated: Feb 17, 2026

Author Spotlight: Quantitative Detection of DNA Protein Crosslinks and Their Post-Translational Modifications
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Author Spotlight: Quantitative Detection of DNA Protein Crosslinks and Their Post-Translational Modifications

Published on: April 21, 2023

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クリック結合型IgG-タンパク質A/Gシステムを用いたDNA改変の普遍的濃縮と配列決定

Junqiu Zhai1, Zhiquan Liu1, Xue Zhang2

  • 1Key Laboratory of Chinese Medicinal Resource from Lingnan, Ministry of Education, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, P. R. China.

Analytical chemistry
|February 16, 2026
PubMed
まとめ

新しい方法であるClick-IP-Seqは,8-オクソ-7,8-ジヒドログアニン (8-オクソ-dG) や5-ヒドロキシメチルシトシン (5hmC) などの改変核酸を効率的に濃縮します. この費用対効果の高いテクニックは,エピジェネティック研究と診断のための多用途の代替案を提供します.

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