ウェアラブル周波数域近赤外線スペクトロスコピー (FD-NIRS) システム
Shashikant Lahade1, Siavash Yazdi2, Nicholas Ross1
1Department of Electrical Engineering, University of Notre Dame, Notre Dame, IN 46556, USA.
Biomedical optics express
|February 16, 2026
まとめ
新しいウェアラブル周波数域近赤外線スペクトロスコーピー (FD-NIRS) システムは,実験室の外で組織酸素化のリアルタイムモニタリングを可能にします. このコンパクトなデバイスは,継続的な健康評価のための非侵襲的な光学スペクトルスコピーを進歩させる.
科学分野:
- バイオメディカル光学
- ウェアラブル・テクノロジー ウェアラブル・テクノロジー
- スペクトル顕微鏡検査です.
背景:
- 周波数域近赤外線光譜法 (FD-NIRS) は,組織構成と代謝を定量化するための非侵襲的な技術です.
- 現在のFD-NIRSの計測器は,しばしば大きく複雑で,研究環境での使用を制限しています.
- 自然的な環境での継続的なモニタリングのために,携帯可能なFD-NIRSシステムが必要である.
研究 の 目的:
- 新しい,リアルタイム,マルチ周波数ウェアラブルFD-NIRSシステムを開発する.
- FD-NIRSテクノロジーを小型化して,健康モニタリングにおけるより広範なアプリケーションを可能にします.
- ウェアラブルアプリケーションの定量的なFD-NIRSの実現可能性を実証する.
主な方法:
- カスタムアプリケーション専用の統合回路 (ASIC) を使用したウェアラブルFD-NIRSシステムを開発しました.
- 685nmと850nmのレーザーダイオードとシリコン光増倍器 (SiPM) 検出器が組み込まれています.
- 組織シミュレーションファントムを使用してシステムの精度を評価し,前腕閉塞測定で概念証明を実証しました.
主要な成果:
- 14.7 Hzの測定速度で,光学特性の高い精度 (吸収: 0.0007 mm−1,分散の減少: 0.08 mm−1) を達成しました.
- ウェアラブルデバイスはコンパクト (7x3x3cm),軽量 (37gバッテリーなし).
- 単一の周波数で最大1kHzのリアルタイム測定機能が実証されています.
結論:
- 開発されたウェアラブルFD-NIRSシステムは,定量的な組織光学スペクトロスコピーの実現可能である.
- この技術は,FD-NIRSのアプリケーションを継続的なモニタリングとナチュラルな環境に拡張することができます.
- このシステムは,ウェアラブルヘルスモニタリングの重要な進歩を表しています.
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