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Updated: Feb 17, 2026

A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles
09:57

A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles

Published on: December 23, 2016

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サイクロデクストリンインクルージョン複合体を含む二相溶解マイクロニードルで,溶解性が低い薬剤の投与を強化します

Runze Wang1, Jiaqi Cao1, Jing Zou1

  • 1School of Pharmaceutical Sciences, Zhengzhou University Zhengzhou Henan China guo5566@126.com.

RSC advances
|February 16, 2026
PubMed
まとめ

この研究では,フルビプロフェン (FB) の皮膚経薬剤投与を強化するために,ヒドロキシプロピル-β-サイクロデクストリン (HP-β-CD) を使用した新しい溶解マイクロニードル (DMN) システムを導入しています. 開発されたDMNは,商用パッチと比較して,薬物の負荷と生物学的利用性を大幅に改善します.

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