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Updated: Feb 17, 2026

Optical Sectioning and Visualization of the Intervertebral Disc from Embryonic Development to Degeneration
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Published on: July 8, 2021

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椎間板変性におけるミトコンドリア駆動フェロプトーシス:年齢関連の脊髄疾患における新しい標的 (レビュー)

Yang Hou1, Xiaolei Yang1, Duorun Qiu1

  • 1Department of Orthopedic Surgery, Changzheng Hospital, Shanghai 200003, P.R. China.

Experimental and therapeutic medicine
|February 16, 2026
PubMed
まとめ

脂質過酸化を含む細胞死プロセスであるフェロプトーシスは,椎間板間変性 (IDD) を引き起こします. ミトコンドリアを標的にすることは,フェロプトーシスを調節することによって,IDDのための新しい治療戦略を提供します.

キーワード:
フェロプトーシス (ferroptosis) とはグルタチオン過酸化酵素4 4椎間板間変性 椎間板間変性ミトコンドリア ミトコンドリア酸化ストレスによるストレスです.

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