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試管受精後の第2 trimester妊娠中絶:リスク要因とリスク軽減

Sarah Rubin¹, Olivia Nussbaum¹, Kaleb Noruzi¹

¹New York Medical College, Valhalla, New York.

|February 16, 2026

まとめ

試管受精 (IVF) の後の第2 trimester loss (STL) は,子宮因子,アデノミオシス,管内不妊,子宮内scaringと関連しています. STLリスクにおける人種的,民族的格差は20年以上も続いている.

科学分野:

生殖医学は,生殖器医学である.
不妊治療の不妊治療について
産科は産婦人科です.

背景:

20年以上にわたり,試験管内受精 (IVF) による選択的単一胚移植の採用は,第2 trimester 損失 (STL) 率に影響を及ぼした可能性があります.
IVF後のSTLの進化の原因を理解することは,妊娠結果を改善するために非常に重要です.

研究の目的:

試験管内受精 (IVF) の後の第2 trimester loss (STL) の割合と潜在的な原因の変化を調査する.
現在のSTL率と関連する要因を1999年から2002年の過去のデータと比較する.

主な方法:

2015年から2023年の間にIVFで妊娠した患者を対象に,遡及的なコホート研究が行われました.
結果は,歴史的なコホートと比較され,複数の妊娠,人種,子宮の欠陥,および管道因子不妊症との関連性について分析されました.

主要な成果:

第2 trimester loss (STL) は,臨床妊娠971例のうち14例 (1.4%) の患者で発生しました.
アデノミオシス,子宮内scaring,および管内因子の不妊症は,STLのリスクの増加と有意に関連していました.
黒人またはヒスパニックと自認する患者は,STLの罹患率が高く,その格差は20年以上にわたってほとんど変わらなかった.

結論:

IVF後のSTLに寄与する要因には,子宮の異常,アデノミオシス,管内不妊,子宮内scaringが含まれます.
STLにおける継続的な人種的,民族的格差は,ターゲットを絞ったリスク予防戦略の必要性を強調しています.
リスクのある集団でIVFを施すSTLを減らすためのカスタマイズされた介入を開発するために,さらなる研究が必要です.

キーワード:

IVFは,IVFで受精するものです.PPROM PPROM は,PPROM と呼ばれるものです.第2トリメスター第2トリメスター損失損失損失損失損失損失損失

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