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Updated: Feb 17, 2026

A Flow Cytometry-Based Cytotoxicity Assay for the Assessment of Human NK Cell Activity
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オステオクラストはNK細胞の抗癌活動に影響する

Clarissa Orrico1,2, Matteo Visca1, Monica Parodi3

  • 1Bone and Dental Bioengineering Lab, Centro Interdipartimentale di Ricerca (CIR) Dental School, Department of Surgical Sciences, University of Turin, Turin, Italy.

Frontiers in immunology
|February 16, 2026
PubMed
まとめ

オステオクラスト (OCs) は自然殺生 (NK) 細胞の活動を低下させ,骨の非小細胞肺がん幹細胞 (NSCLC CSC) の成長を促します. この研究は,NSCLCの骨転移に対する免疫応答を抑制するOCsの役割を明らかにしています.

キーワード:
NK細胞は,NK細胞の細胞である.骨転移による骨転移.がん幹細胞は,がんの幹細胞である.非小細胞肺がんは,小細胞でない肺がんである.オステオクラスト骨格

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