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Updated: Feb 17, 2026

Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade
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Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade

Published on: March 14, 2011

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標準的な免疫抑制療法と併用した低用量のサイクロフォスファミドは,重度のアプラスティック貧血の早期応答率を改善します

Hong Pan1,2,3, Zhen Gao1,2,3, Lele Zhang1,2,3

  • 1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.

Frontiers in immunology
|February 16, 2026
PubMed
まとめ

標準免疫抑制療法 (IST) に低用量サイクロフォスファミド (CTX) を加えることで,重度のアプラスティック貧血 (SAA) 患者における早期応答率が改善されました. この組み合わせ療法は,管理可能な毒性を示し,SAA/VSAA.に対する有望な新しい治療オプションを提供しました.

キーワード:
抗チモサイト・グローブリン (anti-thymocyte globulin) とはサイクロフォスファミド免疫抑制療法による治療です.重度のアプラスティック貧血.トロンボポエチン受容体アゴニスト

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