韓国での貯蔵と加工方法に基づいた母乳の微生物群組成
Changin Oh1, Insoo Kang2, Ben Kang3
1Department of Genetics, Yale School of Medicine, New Haven, CT 06510, USA.
Nutrition research and practice
|February 16, 2026
まとめ
母乳 (HM) を -20°Cで1週間保存し,ボトルウォーマーで解凍すると,有益な微生物群が保存されます. 他の方法は,微生物の組成を大幅に変化させ,乳児の健康に影響を与えます.
科学分野:
- 微生物学 微生物学とは
- 幼児の栄養について
- 人間の牛乳の研究
背景:
- 母乳 (HM) の微生物群は,幼児の発達に不可欠です.
- 貯蔵と解凍中のHM微生物群の保存は不可欠ですが,十分に理解されていません.
研究 の 目的:
- 保存期間,温度,解凍方法がHM微生物群に与える影響を調査する.
- 微生物群の保存のための最適なHM貯蔵と解凍プロトコルを決定する.
主な方法:
- 授乳中の母親からHMサンプルを採取した.
- サンプルを室温,冷蔵庫,および -20°Cで1〜4週間保存する.
- 室温,ボトルウォーマー,マイクロ波の方法を用いてサンプルを解凍した.
- 微生物群の構成と多様性を分析した.
主要な成果:
- 室温で1週間,−20°Cで4週間保存すると,微生物群の多様性が著しく減少した.
- 1週間の -20°Cでの保存は,最初のHMに最も高い微生物の類似性を示しました.
- マイクロ波解凍は,微生物群の組成に最大の変化をもたらしました.
結論:
- HMを -20°Cで最大1週間保存することが推奨されます.
- ボトルウォーマーを使用してHMを解凍することは,好ましい方法です.
- これらの方法は,乳児の健康のために有益なHM微生物群を最も良く保存します.
関連する概念動画
Anatomy of the Intestines
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the small...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the small...
Microbes in Food Production
Microbial fermentation is central to food biotechnology, enhancing flavor, texture, preservation, and stability. Fermentative microorganisms metabolize carbohydrates into organic acids, alcohols, and other metabolites that inhibit spoilage organisms and improve digestibility while contributing distinctive sensory qualities.In baking, amylases naturally present in flour hydrolyze starch into monosaccharides such as glucose, which Saccharomyces cerevisiae ferments anaerobically. Through...
Microbes in the Production of Fermented Foods
Lactic acid bacteria (LAB) and molds are instrumental in fermenting plant-based foods to enhance preservation and ensure year-round availability. These microbial processes convert plant carbohydrates into organic acids and other metabolites that inhibit spoilage organisms and contribute to the sensory qualities of the final product.In sauerkraut production, cabbage goes through a microbial succession that starts with cocci such as Leuconostoc mesenteroides. These microbes begin fermentation by...
Introduction to the Human Microbiota
Microorganisms colonize various regions of the human body, including the mouth, nasal passages, throat, stomach, intestines, urogenital tract, and skin. The total number of microbial cells is estimated to range from 10¹³ to 10¹⁴—comparable to, or exceeding, the number of human somatic cells. This host–microbiome relationship has led to the conceptualization of humans as supraorganisms, wherein microbial communities perform vital roles in development, immunity, and disease...
Development of Human Microbiota
The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...
Development of the Oral Microbiota
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...


