妊娠中の有毒性表皮性ネクロリシス:症例報告
Anisha Choudhary1, Murari Bharadwaj2, Archana Barik1
1Obstetrics and Gynecology, Tata Main Hospital, Jamshedpur, IND.
Cureus
|February 16, 2026
まとめ
スティーヴンズ・ジョンソン症候群 (SJS) や毒性表皮解体 (TEN) などの重度の副作用は,妊娠中にまれである. このケースは,ハーブ医薬品からTENを示し,母親と胎児の迅速な認識と多学科的ケアの必要性を強調しています.
科学分野:
- 皮膚科 皮膚科について
- 毒理学 毒理学 毒理学
- 産科は産婦人科です.
背景:
- スティーヴンズ・ジョンソン症候群 (SJS) と有毒性表皮解体 (TEN) は,重症で稀な粘膜皮質による薬剤副作用であり,高い罹病率と死亡率を有する.
- 妊娠はSJS/TENの診断と管理にユニークな課題をもたらし,母親と胎児の両方にリスクをもたらす.
研究 の 目的:
- 妊婦の有毒性表皮解剖 (TEN) の症例を報告する.
- 妊娠中のTENの診断と管理の課題について議論する.
- 薬草薬剤に関連する潜在的なリスクを強調するために.
主な方法:
- 妊娠29週目の25歳の女性で,広範囲に広がった皮膚発疹を呈した症例報告.
- TENの診断は,臨床的特徴,表皮脱落の程度,およびハーブ医薬品の摂取と一時的な関連に基づいています.
- システミックなコルチコステロイド,サポートケア,個別化産婦人科管理を含む多学科的管理.
主要な成果:
- 患者は,処方箋外薬の薬草薬を摂取した後にTENと診断されました.
- 彼女は,自発的な早産経由で陰間経由で男性新生児を産んだ.
- 母親と新生児の両方が,漸進的な臨床改善と完全な再上皮質化とともに,好ましい結果を経験しました.
結論:
- 妊娠中のTENの早期臨床認識は極めて重要です.
- 薬草および代替薬剤は,重度の皮膚不良反応を早めることができます.
- 違反剤の迅速な除去,多学科的ケア,そして適正な産科管理は,母親と胎児の最適な結果のために不可欠です.
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