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Updated: Feb 17, 2026

Surface Engineering of Pancreatic Islets with a Heparinized StarPEG Nanocoating
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接触するか否か:ヒトインスリンとのポリマー表面相互作用とその治療的影響に関する調査

Megren H A Fagihi1,2,3, Chanaka Premathilaka4, Laura Zopf2,5

  • 1School of Medicine, University College Dublin Belfield, Dublin 4 Ireland.

RSC advances
|February 16, 2026
PubMed
まとめ

インスリンとポリマーの間の相互作用は,インスリンを凝集させ,糖尿病治療の有効性を低下させる可能性があります. アミン末端のポリマーは,酸末端のポリマーと比較して,より大きなインスリン凝集とより大きなpH変化をもたらしました.

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