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Updated: May 6, 2026

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MUC20は,MET/RAS/STING軸を通してピロプトーシスを調節することによって腎臓線維症を緩和します

Jiaxin Huang1, Zhoutong Chen1, Fengbo Zhong2

  • 1Department of Urology, Children's Hospital of Fudan University, Shanghai, 201102, China.

Theranostics
|February 16, 2026
PubMed
まとめ

ムシンMUC20は,RAS-STING-NLRP3経路を調節することにより,腎臓を線維症と細胞死から保護します. MUC20の喪失は腎臓損傷を悪化させ,腎臓疾患の治療標的としてMUC20を示唆しています.

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