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Updated: Feb 17, 2026

Evaluating Therapeutic Interventions in the SHIP-deficient Mouse Model of Crohn Disease-like Ileitis and Fibrosis
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IFIH1の機能喪失変異が感染性および/または炎症性疾患にどのように貢献するか - システマティック・レビュー

Isabelle Ince1, Francesca Sposito1, Amandine Charras1

  • 1Department of Women's and Children's Health, Institute of Life Course and Medical Sciences, University of Liverpool, UK.

Journal of translational autoimmunity
|February 16, 2026
PubMed
まとめ

IFIH1遺伝子 (MDA5をコードする) の機能喪失変異は,ウイルス感染症に対する感受性を高めますが,炎症性疾患から保護することができます. これはIFIH1を強調しています.

キーワード:
欠点 欠点 欠点 欠点病気 病気 病気IFIH1は,IFIH1に該当する.感染症 感染炎症 炎症 炎症 炎症 炎症インターフェロン (インターフェロン) は,MDA5 MDA5 MDA5 は,MDA5 を使っている.

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