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メセントリック・キャステルマン病: 2つの症例報告と文献レビュー

Se-Niu Jizhi^1,2, Xing-Yu Chen², Shan-Shan Wu²

¹Department of Clinical Medicine, North Sichuan Medical College, Nanchong 637000, Sichuan Province, China.

World journal of gastrointestinal surgery

|February 16, 2026

まとめ

メセントリックカステルマン病 (CD) は珍しい. この研究では,外周T細胞リンパ腫 (PTCL-NOS) に変容する2つの症例を詳細に説明し,さまざまな臨床経過とパーソナライズされた管理の必要性を強調しています.

科学分野:

腫瘍学腫瘍学
胃腸内科胃腸内科
病理学パトロジー

背景:

カステルマン病 (Castleman disease,CD) は,珍しいリンパ増殖性疾患である.
メセンテリア性CDはまれで,典型的には組織病理学で診断されます.
胃腸症状と体重減少は,中腸関節の関与を示唆する可能性があります.

研究の目的:

メゼンテリックカステルマン病の2つのユニークな症例を報告します.
メゼンテリックCDが周辺T細胞リンパ腫 (PTCL-NOS) に変容する可能性を強調する.
メゼンタリックCDのパーソナライズされた治療戦略の重要性を強調するために.

主な方法:

メゼンタリックCDを患った2人の患者の症例報告.
診断と分類のための外科的切除と組織病理学的検査.
病気の経過と治療の結果を評価するための臨床フォローアップ.

主要な成果:

ケース1:ヒアリン血管型CD,切開後の予後は好ましい.
ケース2:最初はプラズマ細胞型CDで,PTCL-NOSに変形した.
ケース2は,PTCL-NOSによる再手術後の死亡率につながる攻撃的な経路を経験しました.

結論:

これは,メゼンテリックCDがPTCL-NOSに変異した最初の報告例です.
メセンテリックCDは,複雑で異質な臨床行動を示す.
発見は,メゼンタリックCDの特化した治療と管理アプローチを強調しています.

キーワード:

ケースレポートケースレポートカステルマン病はカステルマン病です.免疫ヒストキミストリーメセンテリア Mesentery メセンテリア周辺のT細胞リンパ腫

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