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Updated: Feb 17, 2026

Direct Lineage Reprogramming of Adult Mouse Fibroblast to Erythroid Progenitors
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再結合エリトロポエチン発現は,CHO DG44細胞における至るところに存在するクロマチンの開口要素 (UCOE) によって上昇する

Fateme Hasheminejad1, Haniyeh Norouzi1,2, Seyede Hoda Jazayeri3

  • 1Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.

Biotechnology letters
|February 16, 2026
PubMed
まとめ

どこにでも存在するクロマチンの開き要素 (UCOE) は,CHO細胞における再結合タンパク質の生産を著しく促進する. この方法は,遺伝子サイレンシングを克服し,バイオ医薬品の製造効率を改善することによって,エリトロポエチン (EPO) 発現を強化します.

キーワード:
CHODG44 (コハDG44) についてエリトロポエチンは,リコンビナントタンパク質は,どこにでも存在するクロマチンの開口要素.

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