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Updated: Aug 16, 2026

Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders
07:40

Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders

Published on: April 14, 2017

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SNCAのトリプリケーションは,人間の中脳オルガノイドの神経変性以前にプロテオスタシスと細胞外構造を乱します

Elpida Statoulla1, Maria Zafeiri1, Kleanthi Chalkiadaki1

  • 1Biomedical Research Institute, Foundation for Research and Technology-Hellas, Ioannina, Greece.

NPJ Parkinson's disease
|February 16, 2026
PubMed
まとめ

パーキンソン病のモデルにおける初期の分子変化には,タンパク質合成と細胞外マトリックス組織が変化することが含まれます. 人間の中脳オルガノイドにおけるこれらの発見は,神経変性発症に先立つ重要な出来事を明らかにする.

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Human Neural Organoids for Studying Brain Cancer and Neurodegenerative Diseases

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Robust and Highly Reproducible Generation of Cortical Brain Organoids for Modelling Brain Neuronal Senescence In Vitro05:40

Robust and Highly Reproducible Generation of Cortical Brain Organoids for Modelling Brain Neuronal Senescence In Vitro

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