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遺伝的にコードされた二機能酵素は,酸化還元不均衡と脂質毒性を軽減します

Xingxiu Pan1, Subrata Munan1, Austin L Zuckerman1,2,3

  • 1Scintillon Institute, Laboratory of Redox Biology and Metabolism, San Diego, CA, USA.

Nature metabolism
|February 16, 2026
PubMed
まとめ

新しく開発されたChlamydomonas reinhardtii glycerol-3-phosphate dehydrogenase (CrGPDH) は,細胞の酸化還元バランスとリポゲネシスを効果的に管理しています. この酵素は,様々な細胞タイプとマウスモデルにおける還元ストレスとトリグリセリドの蓄積を緩和します.

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