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Updated: Feb 18, 2026

Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs
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Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs

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集積された濃度データから集団レベルの薬理動力学的パラメータを推定するための物理情報に基づくニューラルネットワークアプローチ

Periklis Tsiros1, Vasileios Minadakis1, Haralambos Sarimveis2

  • 1School of Chemical Engineering, National Technical University of Athens, 9 Iroon Polytechniou Str, Zografou Campus, 15772, Athens, Greece.

Journal of pharmacokinetics and pharmacodynamics
|February 16, 2026
PubMed
まとめ

この研究では,集合濃度データから集団の薬動学パラメータ分布を抽出するために,分布物理情報ニューラルネットワーク (D-PINNs) を導入します. D-PINNは,概要統計からパラメータ分布と残余エラーを正確に回復し,薬理学モデリングを進める.

キーワード:
ODEsは,ODEとして使用されます.ピンインズ (PINNS) とはファルマコキネティクス統計モデリング 統計モデリング

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