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Updated: Feb 18, 2026

Improved In-gel Reductive β-Elimination for Comprehensive O-linked and Sulfo-glycomics by Mass Spectrometry
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希少な3-O-硫化パターンの解鎖は,ARSG指向型地域選択的脱硫とHILIC-MSを通じてヘパラン硫酸で示されています

Salomé Poyer1, Agnès Denys2, Nesrine El Omrani1

  • 1Université Paris-Saclay, Univ Evry Paris-Saclay, CY Cergy Paris Université, CNRS, LAMBE, 91025 Evry-Courcouronnes, France.

Analytical chemistry
|February 17, 2026
PubMed
まとめ

ヒューマンリゾソーマアルシルファタゼG (ARSG) は,希少な3-O硫酸ヘパラン硫酸 (HS) モチーフの識別を可能にします. この新しい酵素ツールが,高度な染色法と組み合わせて,病気におけるHS構造-機能関係を理解するのに役立ちます.

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