後部可逆性脳性病症候群の症例で,胸椎脊髄の下部血腫を合併させた
Tamotsu Gotou1,2, Yuto Munemura1, Takahiro Hagihara1
1Department of Emergency and Critical Care Medicine, Tottori Prefectural Central Hospital, Tottori, JPN.
Cureus
|February 17, 2026
まとめ
後部逆転性脳病症候群 (PRES) は,脊髄血腫とともにまれに発生することがあります. 迅速な血圧制御と脳MRIは,この珍しい臨床シナリオでPRESの診断と管理に不可欠です.
科学分野:
- 神経学 神経学とは
- 放射線学 放射線学
- クリティカルケア・メディシン
背景:
- 後部可逆脳症候群 (後部可逆脳症候群,PRES) は,神経学的症状と特徴的な脳イメージングの発見によって特徴づけられる臨床放射線学的状態です.
- PRESの一般的な原因は知られているが,脊髄血腫との関連は極めてまれである.
研究 の 目的:
- PRESを合併する脊髄血腫の稀な症例を報告するためです.
- 潜在的なトリガーを強調し,迅速な診断と管理の重要性を強調する.
主な方法:
- 腰痛,高血圧,神経学的症状を呈する68歳の男性に関する症例報告.
- 診断作業には,胸脊髄MRIと脳MRIが含まれていました.
- 管理には,集中治療室のモニタリングと,継続的な抗高血圧注入と鎮痛薬/鎮静薬を含む.
主要な成果:
- 患者は重度の高血圧,発作,頭痛,視力障害を発症した.
- 胸部脊椎のMRIは脊髄の下部血腫を明らかにし,脳MRIはPRESを確認しました.
- 神経学的症状は,血圧のコントロールとサポートケアによって解決しました.
結論:
- PRESは,脊髄血腫の珍しいが可能な合併症です.
- 潜在的なトリガーは,痛みに関連した高血圧,自律機能不全,および流体不均衡を含む.
- 迅速な認識,血圧管理,脳イメージングは,脊髄血腫の患者でPRESが疑われる場合に不可欠です.
関連する概念動画
Hemorrhagic Stroke l: Introduction
20
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
20
Hemorrhagic Stroke ll: Pathophysiology
30
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
30
Encephalitis l: Introduction
15
Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
15
Brain Abscess l: Introduction
21
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial...
21
Cerebral Edema ll: Pathophysiology
19
Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this...
19
Hepatic Encephalopathy
53
DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic...
53


