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Updated: Feb 18, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Published on: August 16, 2018

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α5-GABAAアロステル調節は,AMPA受容体経由でドーパミンのニューロン活動を誘発し,延長する

Areebah Ahmed1, Mostafa El Mansari1, Pierre Blier1

  • 1Institute of Mental Health Research, University of Ottawa, ON, Canada.

Journal of psychopharmacology (Oxford, England)
|February 17, 2026
PubMed
まとめ

α5-GABAA受容体調節剤L-655,708は,ラットのドーパミンニューロン活動を最大1週間増加させます. この抗うつ剤のような効果はAMPA受容体とベンゾジアゼピンサイトによって媒介されます.

キーワード:
L-655,708 について抗うつ剤の抗うつ剤は,抗うつ薬として使われています.ドーパミンは,ドーパミンです.ノルアピネフリン (norepinephrine) とは,ノルアピネフリン (norepinephrine) とは,ノルアピネフリン (norepinephrine) とは,ノルアピネフリン (norepinephrine) とは,ノルアピネフリン (norepinephrine) とは,ノルアピネフリン (norepinephrine) とは,ノルアピネフリン (norepinephrine) とは,ノルアピネフリン (norepinephrine) とはセロトニン・セロトニンとは

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