転移性パピラリ甲状腺がんの皮膚表情

Joseph H Kelly¹, Elise V H Meide¹, Brian J Tjarks²

¹Sanford School of Medicine, University of South Dakota, Sioux Falls, SD; and.

The American Journal of dermatopathology

|February 17, 2026

まとめ

パピラ性甲状腺癌は皮に広がることはめったにありませんが,それが起こると,広範囲に広がった病気を示します. このケーススタディは,若い女性の孤立した皮膚転移の希少な事例を示しています.

科学分野:

腫瘍学腫瘍学
皮膚科皮膚科について
病理学パトロジー

背景:

papillary thyroid carcinoma (PTC) は,一般的に好ましい予後を伴う一般的な甲状腺悪性腫瘍です.
PTCの転移は通常,リンパ節,肺,または骨を含む.
PTCによる皮膚転移は稀であり,進行した疾患と悪い結果と関連しています.

研究の目的:

皮膜性甲状腺がんの異常な症例を報告する. 皮膜性甲状腺がんの異常な症例を報告する. 皮膜性甲状腺がんの異常な症例を報告する. 皮膜性甲状腺がんの異常な症例を報告する.
PTCにおける皮膚の関与の診断上の課題と予後的な影響について議論する.

主な方法:

症例報告は,臨床プレゼンテーション,診断作業,および組織病理学的発見を詳細に記載しています.
皮質性甲状腺がんの皮膚転移に関する関連する文献のレビュー.

主要な成果:

患者は若い女性で,孤立した皮膚病変を呈した.
組織病理学と免疫ヒストケミストリーは,この病変がパピラリ甲状腺がんの転移であることを確認した.
転移の位置と孤立した性質は,PTCの拡散に非典型的でした.

結論:

皮質性甲状腺がんの皮膚転移は稀ですが,孤立した病変として発生することがあります.
このプレゼンテーションは,既知の原発性疾患がない場合でも,皮膚病変の微分診断において,転移性PTCを考慮することの重要性を強調しています.
孤立した皮膚転移は,広範囲に広がった病気を意味し,予後不良を予告する可能性があります.

キーワード:

PAX8はPAX8と一致しています.TTF-1 (タートルズ・フォー・フィクション・ユニット)皮膚転移による転移です.遅い再発遅い再発 papillary thyroid carcinoma (パピラリー甲状腺がん) が発症している.皮膚の新生体である皮膚腫瘍.単発性皮膚病変による単発性皮膚病変

さらに関連する動画

03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

1.1K

07:01

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

Published on: April 17, 2013

21.7K

関連する概念動画

01:30

Skin Cancer

6.2K

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

6.2K

01:11

Papillary Dermis

6.1K

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...

6.1K

01:23

Skin Diseases and Disorders

5.8K

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

5.8K

02:30

Metastasis

6.7K

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

6.7K

01:23

The Thyroid Gland

7.9K

The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...