日本人の高齢者の口腔の弱さと社会的弱さ
Isi Susanti1,2, Hazem Abbas2, Kenji Takeuchi2,3
1Department of Community Dentistry of Chulalongkorn University, Bangkok, Thailand.
Gerodontology
|February 17, 2026
まとめ
口腔不全 (OF) は,高齢の日本人の社会不全 (SF) と関連しています. 口腔健康への取り組みは,高齢者の社会的脆弱性を軽減するのに役立ちます.
科学分野:
- ゲロントロジーはゲロントロジーの学科です.
- 公衆衛生は公衆衛生である.
- 口腔衛生は,口腔の健康についてです.
背景:
- 社会的な弱さ (SF) は,高齢者集団の間でますます懸念され,全体的な福祉に影響を及ぼしています.
- 口腔不全 (OF) は,高齢者の日常生活に影響を与える可能性のある様々な口腔健康問題を網羅しています.
- 口腔の健康と社会的つながりの相互作用を理解することは,高齢者ケアにおいて極めて重要です.
研究 の 目的:
- 日本における独立した,コミュニティに住む高齢者における口腔脆弱性 (OF) と社会脆弱性 (SF) の関連性を調査する.
- 社会的弱さに寄与する口腔の弱さの特定の構成要素を特定する.
主な方法:
- 横断的な研究では,2022年のJAGES波から,65歳以上で機能的に独立した日本人の19,319人のデータを利用しました.
- 口腔の脆弱性は,カテゴリ変数,5つの構成要素のカウントスコア,個々の構成要素,および組み合わせた口腔機能変数を使用して評価されました.
- 社会的な脆弱性は,5項目の指数 (SF-5) を使用して測定されました. 調整されたオーダーされたロジスティック回帰モデルが採用されました.
主要な成果:
- 口腔の脆弱性と社会的脆弱性との間に有意な関連性が見られ,OFの個体ではSFの確率が高く見られた.
- 最も高い口腔脆弱性スコア (スコア 5) は,社会的脆弱性 (OR 2.53) の確率が最も高いことを示した.
- 口の乾燥 (OR 1.29) と4つの口腔機能の低下 (OR 2.42) は,社会的弱さと強く関連していました.
結論:
- 口腔の脆弱性とその構成要素は,高齢の日本人の社会的脆弱性と有意に関連しています.
- 結果は,口腔機能の低下に起因する社会的脆弱性に対処するために,統合されたスクリーニングと予防戦略の必要性を示唆しています.
- 口腔衛生を対象とした介入は,高齢者の社会的孤立と脆弱性を軽減する役割を果たす可能性があります.
関連する概念動画
Aging
874
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
874
Pharmacodynamics in Geriatric Patients: Effects of Age
244
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
244
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism
235
Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
235
Bone Disorders
5.6K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.6K
The Effect of Aging on Tissues
3.8K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
3.8K
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
272
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
272


