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Updated: May 9, 2026

High-Throughput In Vitro Assay using Patient-Derived Tumor Organoids
06:25

High-Throughput In Vitro Assay using Patient-Derived Tumor Organoids

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ヒューマン・オルガノイド・ドラッグ・センシビティ・テストを用いたHER2陽性肺腺癌のパーソナライズされた治療

Tao Luan1,2,3,4, Suneng Fu1,4, Weiting Liu1,5

  • 1National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Human vaccines & immunotherapeutics
|February 17, 2026
PubMed
まとめ

症例研究では,ヒト表皮成長因子受容体2 (HER2) -変異性肺がんにおける抗体-薬物結合療法に対する耐性の課題が強調されています. ヒューマン・オルガノイド・ドラッグ・センシビティ・テスト (HO-DST) は,サンボゼルチニブを有望な救済療法オプションとして特定しました.

キーワード:
薬物感受性テスト (DST)ヒューマン・オルガノイド (HO)バイオミメティクス バイオミメティクス肺がんは肺がんである.

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