関連する実験動画

Updated: Feb 19, 2026

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
11:19

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels

Published on: July 4, 2016

11.1K

マグネシウムチャネルCORAのコンフォームアンサンブルは,チャネルゲーティングの構造的基礎を明らかにしています

Satchal K Erramilli1, Kamil Nosol1, Krzysztof Pietrzak-Lichwa1,2

  • 1Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637.

Proceedings of the National Academy of Sciences of the United States of America
|February 17, 2026
PubMed
まとめ

CorAチャネルは,プロカリオットのマグネシウム流入を調節する. 構造の研究は,マグネシウムレベルによって制御される構成組を明らかにし,チャネルアシンメトリーと細胞ホメオスタシスのゲーティングを結びつける.

キーワード:
チャンネルゲーティング (Channel gating) とはクリオ・エム・エム (cryo-EM) とはイオンチャネルイオンチャネル膜タンパク質構造 膜タンパク質構造合成抗体である.

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