PHACE症候群における神経イメージングの発見の長期的な進化に関する多センター研究
Elizabeth George1, Mitchell Braun2, Rachel Vassar3
1Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
まとめ
PHACE症候群の子供のほぼ3分の1が進行性脳血管動脈病変を経験しています. 長期イメージングは,この進行を示していますが,PHACE患者では脳卒中はまれです.
科学分野:
- 神経皮質疾患 神経皮質疾患
- 小児神経学 小児神経学
- 血管の異常について
背景:
- PHACE症候群 (後方穴の異常,血管腫,動脈の異常,心臓の異常,目の異常) は,複雑な神経皮質疾患である.
- 頸動脈異常は,長期的な監視を必要とする重要な特徴です.
研究 の 目的:
- PHACE症候群における長期的な神経イメージングの進化を評価するために.
- 動脈病変と頭蓋内血球腫の進行に焦点を当ててください.
主な方法:
- 16のサイトで83人のPHACE患者からの神経イメージングの遡及的レビュー.
- 最初のスキャン (約1歳) と,最新のスキャン (平均14歳) の比較.
- 構造的異常,心臓発作,血管異常,進行性動脈病の評価.
主要な成果:
- 進行性動脈病変は患者の29.4%で観察され,7%のモヤモヤを含む.
- 初期血管リスクスコアは,動脈病変の進行を予測できませんでした.
- 頭蓋内血球腫は,メッケル洞窟の拡大と関連しており,インボリューション的変化を示唆しています.
結論:
- PHACE患者の有意な割合は,時間の経過とともに進行性脳血管動脈症を発症する.
- 脳卒中は稀ですが,動脈病変の進行のリスクは,最適な監視戦略のさらなる調査を正当化します.
キーワード:
動脈病気が発症する.MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,MRA,M神経皮質性 神経皮質性PHACE (ペース) とは血管病は,血管病である.さらに関連する動画
関連する概念動画
01:24Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
01:15Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT) is an advanced Nuclear Magnetic Resonance (NMR) technique specifically designed to detect and enhance the signals of low-abundance nuclei, such as carbon-13 and nitrogen-15, in small molecules. The fundamental principle behind INEPT is the transfer of polarization from a more abundant and highly polarizable nucleus, typically hydrogen-1, to the low-abundance nucleus of interest. This process effectively boosts the NMR signal of the...
01:14Imaging Studies I: CT and MRI
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
01:25Imaging Studies II: Positron Emission Tomography and Scintigraphy
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Fundamental Principles of PET
01:14Brain Imaging
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
01:27Imaging Studies IV: Magnetic Resonance Imaging
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...