関連する実験動画

Updated: Feb 19, 2026

Dynamic Clamp Methods to Investigate Impaired Neuronal Excitability Associated with Autism
08:44

Dynamic Clamp Methods to Investigate Impaired Neuronal Excitability Associated with Autism

Published on: October 17, 2025

736

ノッチとNerfin-1によるアクションポテンシャル波形のホメオスタティック保存

Daniel Karmelic1, Yelena Steinberg2, Ryan T Jones3

  • 1Department of Biochemistry and Biophysics, Kavli Institute for Fundamental Neuroscience (KIFN), University of California, San Francisco, San Francisco, CA 94143, USA.

Current biology : CB
|February 17, 2026
PubMed
まとめ

ニューロンは,Notch/Nerfin-1シグナル伝達経路を通じて特定の発火パターンを維持する. このシステムは,カリウムチャネル喪失後のアクションポテンシャル波形を正確に復元し,安定した脳活動を保証します.

キーワード:
新興の不動産資産である.発火速度ホメオスタシス ホメオスタシスホメオスタシス (homeostasis) とは本質的な興奮力である.イオンチャネルイオンチャネルプレセニリン プレセニリン

さらに関連する動画

Focal Macropatch Recordings of Synaptic Currents from the Drosophila Larval Neuromuscular Junction07:01

Focal Macropatch Recordings of Synaptic Currents from the Drosophila Larval Neuromuscular Junction

Published on: September 25, 2017

6.5K
The Preparation of Oblique Spinal Cord Slices for Ventral Root Stimulation09:10

The Preparation of Oblique Spinal Cord Slices for Ventral Root Stimulation

Published on: October 13, 2016

10.3K

関連する概念動画

Action Potentials01:41

Action Potentials

Overview
143.6K
Action Potential01:14

Action Potential

Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
11.5K
Action Potential01:31

Action Potential

Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
4.9K
Propagation of Action Potentials01:23

Propagation of Action Potentials

The propagation of an action potential refers to the process by which a nerve impulse, or "action potential," travels along a neuron.
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
9.9K
Resting Potential Decay01:15

Resting Potential Decay

The resting membrane potential of a neuron (-70mV) is sustained due to the selective ion permeability of the membrane. At the resting potential, the membrane is slightly permeable to ions like sodium (Na+) and chloride (Cl−) and highly permeable to potassium ions (K+). Differences in the ions' concentration inside the cell compared to the outside are maintained by membrane transport proteins like channels and pumps.
At rest, the K+ is the main ion that moves across the membrane...
6.5K
Action Potential: Phases of Stimulation01:28

Action Potential: Phases of Stimulation

The action potential is a complex electrical event that occurs in excitable cells, such as neurons and muscle cells. It consists of several distinct phases, each with specific characteristics.
Resting Phase:
In this phase, the cell's membrane is at its resting potential, typically around -70 millivolts (mV) for neurons. Inside the cell, there is a higher concentration of potassium ions (K+) and a lower concentration of sodium ions (Na+). Voltage-gated sodium channels are closed, and...
12.9K