関連する実験動画

Updated: Feb 19, 2026

Substrate Generation for Endonucleases of CRISPR/Cas Systems
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Substrate Generation for Endonucleases of CRISPR/Cas Systems

Published on: September 8, 2012

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タイプII-AのCRISPR-CasシステムにおけるCas9指向のスペーサー取得のための構造的基礎

Zhaoxing Li1, Yutao Li2, Jianping Kong2

  • 1State Key Laboratory of Natural Medicines, School of Pharmacy, China Pharmaceutical University, Nanjing, China; Chongqing Innovation Institute, China Pharmaceutical University, Chongqing 401135, China; Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore 117543, Singapore.

Molecular cell
|February 17, 2026
PubMed
まとめ

CRISPR-Cas9システムは,Cas9,Csn2,Cas1-Cas2を使用して,外来DNAを取得しています. Cryo-EMは,これらのタンパク質がDNAを認識し,プロカリオット免疫の正確な統合を確保する方法を示しています.

キーワード:
CRISPRは,CRISPRを活用して研究しています.カス1 カス1 カス1カス9はカス9です.スパッサーの買収

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