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Updated: Feb 19, 2026

Novel RNA-Binding Proteins Isolation by the RaPID Methodology
11:19

Novel RNA-Binding Proteins Isolation by the RaPID Methodology

Published on: September 30, 2016

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サークRNAと標的RNAの相互作用のグローバルマッピングは,P-body媒介の翻訳抑制を明らかにしています

Peng Li1, Hongmei Zhang2, Zhaokui Cai1

  • 1State Key Laboratory of Epigenetic Regulation and Intervention, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

Molecular cell
|February 17, 2026
PubMed
まとめ

この研究では,円形のRNA (circRNA) ターゲットをマッピングするためのコンピューティングツールであるcircTargetMapを紹介しています. それは,circRNAsが細胞粒子の内部に標的mRNAを結合することによって遺伝子発現を調節し,潜在的に病気に影響を及ぼすことを明らかにします.

キーワード:
P-bodies (P体) とは,P体と呼ばれるものです.RIC-seqqは,RIC-seqqと一致している.RNAとRNAの相互作用RNA結合タンパク質は,RNAを結合するタンパク質です.円形のRNARNAを循環させる.粒子のRIC-seqqが使われています.翻訳的な抑圧

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