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Updated: Feb 19, 2026

Isolation of Peritoneum-derived Mast Cells and Their Functional Characterization with Ca2+-imaging and Degranulation Assays
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Isolation of Peritoneum-derived Mast Cells and Their Functional Characterization with Ca2+-imaging and Degranulation Assays

Published on: July 4, 2018

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細胞粘着分子1は結合組織のマスト細胞で上調され,IgE媒介による脱粒化に潜在的に寄与する

Man Hagiyama1, Azusa Yoneshige2, Fuka Takeuchi1

  • 1Department of Pathology, Faculty of Medicine, Kindai University, Osaka, 589-8511, Japan.

Scientific reports
|February 17, 2026
PubMed
まとめ

細胞粘着分子1 (CADM1) は,結合組織幹細胞 (CTMC) の脱粒化を調節する. CADM1を標的にする新型抗体3E1は,マスト細胞の活性化とデグラヌレーションを抑制し,マスト細胞の異質性に関する洞察を提供した.

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