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Updated: Feb 19, 2026

One-channel Cell-attached Patch-clamp Recording
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Published on: June 9, 2014

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2段階のクロックワークメカニズムにより,PIEZO2のタンパク質脂質孔が開きます

Shu Li1, Tharaka Wijerathne2, Aashish Bhatt3

  • 1Centre for Artificial Intelligence Driven Drug Discovery, Faculty of Applied Sciences, Macao Polytechnic University, Macao SAR, China.

Nature chemical biology
|February 17, 2026
PubMed
まとめ

機械的に敏感なPIEZOチャネルは,2段階のメカニズムを通過し,腕を平らにし,毛穴をねじます. これは,PIEZO2チャネル活性化と緊張下での機能の構造的基礎を明らかにします.

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