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Updated: Feb 19, 2026

Three-dimensional Imaging of Nociceptive Intraepidermal Nerve Fibers in Human Skin Biopsies
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修正：神経腫の痛みを予測する線維構造の維持：形態学的研究

Luis A Pardo1,2, Carolina Thomas3,4, Arndt F Schilling5

  • 1Hannover Medical School, Department of Trauma Surgery, Hannover, Germany. PardoSanchez.Luis@mh-hannover.de.

Acta neuropathologica communications
|February 18, 2026
PubMed
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No abstract available in PubMed .

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Local Anesthetics: Differential Sensitivity of Nerve Fibers

Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
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