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永続的な炎症,免疫抑制,そしてカタボリックシンドローム: 増大する問題に対する新たな見方
Sara Scarlet1, Erin Vanzant1, Letita Bible1
1Department of Surgery, Division on Acute Care Surgery, University of Florida, Gainesville, Florida, USA.
まとめ
重症の患者は,持続的な炎症,免疫抑制,およびカタボリックシンドローム (PICS-1) を発症することがあります. このレビューでは,PICS-1患者のための栄養支援戦略を調査し,現在のエビデンスベースのガイドラインのギャップに対処しています.
科学分野:
- クリティカルケア・メディシン
- クリニカル・ニュートリション
背景:
- 栄養補助は重症患者のために不可欠です.
- 増加する患者集団は,継続的な炎症,免疫抑制,および多器官機能不全の状態であるカタボリックシンドローム (PICS-1) を表しています.
- 集中治療管理の改善により,生存率が増加し,PICS-1がより一般的になった.
研究 の 目的:
- PICS-1の起源と流行病学について説明する.
- PICS-1患者のための潜在的な栄養サプリメントの検討.
- PICS-1.の具体的なエビデンスに基づく栄養ガイドラインの欠如に対処するためです.
主な方法:
- PICS-1を中心とした文献レビュー.
- PICS-1集団の流行病学的な議論.
- PICS-1に関連した栄養介入の調査.
主要な成果:
- PICS-1は,重症の生存者における新興症候群である.
- 現在の文献では,PICS-1の栄養支援に関する具体的なガイドラインが不足しています.
- 潜在的な栄養戦略は,臨床結果に影響を与える可能性があります.
結論:
- PICS-1は,さらなる研究を必要とする独特の臨床実体を表しています.
- PICS-1患者のためのエビデンスベースの栄養支援プロトコルが必要です.
- ターゲティングされた栄養補助食品に関するさらなる研究が必要である.
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