関連する実験動画

Updated: Feb 19, 2026

Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay
09:07

Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay

Published on: December 19, 2018

6.8K

エストロゲン受容体リガンド結合ドメインテトレメリゼーションのアロステリック誘導は,明確な完全なエストロゲン受容体アンタゴニストによって行われる

Emma C Fink1, Reena Chawla2, Govinda R Hancock1

  • 1Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois 60546, United States.

ACS medicinal chemistry letters
|February 18, 2026
PubMed
まとめ

新しい研究で,ER+乳がんのための新しい完全なエストロゲン受容体対抗剤 (CERAN) OP-1690が紹介されています. この化合物は独特にERαテトラマーを形成し,従来の治療法を超えた新しい治療法を提供します.

キーワード:
セラン (CERAN) とは核受容体受容体についてエストロゲン受容体エストロゲン受容体ホルモン ホルモン ホルモン ホルモン ホルモン非ステロイド性である.オリゴメリゼーションによるオリゴメリゼーション.

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