クリプトグランデュラアナルフィスラコアアウトカム測定セット (AFCOMS):標準化された定義と測定器具
Nedim Tabakovic1,2, Shivani Joshi3, Merel Kimman4
1Department of Surgery and Colorectal Surgery, Maastricht University Medical Centre+, the Netherlands.
EClinicalMedicine
|February 18, 2026
まとめ
アナルフィスティラ研究のための新しいコア・アウトカム・メジャーメント・セット (COMS) は,アウトカム定義と測定ツールを標準化しています. これにより,暗号腺性門フィスチュラ研究における一貫性とエビデンス合成が改善されます.
科学分野:
- 胃腸内科 胃腸内科
- 手術研究の研究について
- 患者の報告したアウトカム
背景:
- 暗号腺性門門は,患者の生活の質に大きな影響を与えます.
- 既存のアナル・フィスラ・コア・アウトカム・セット (AFCOS) には,標準化されたアウトカム・定義と測定器具がなく,研究の比較性が妨げられています.
- 将来のエビデンス・シンセシスを改善するために,AFCOSと整合したコア・アウトカム・メジャーセット (COMS) が必要です.
研究 の 目的:
- 国際的なコンセンサス主導のコア・アウトカム・メジャーメント・セット (Core Outcome Measurement Set,COMS) を確立し,暗号腺性門門研究を行うこと.
- COMSを既存のアナルフィスラ・コア・アウトカム・セット (AFCOS) と一致させる.
- 研究の一貫性を高めるために,成果の定義と測定器具を標準化する.
主な方法:
- COMETの方法論に従った3段階の研究.
- 第1段階:AFCOSの成果の定義と手段の範囲見直し. 第2段階:COSMIN基準を用いたサイコメトリック特性の評価. 第3段階:国際デルフィ二回戦調査と,患者と医療従事者とのコンセンサス会議.
- 定義,測定器具 (アナルフィッスル生活の質スケール,ヴァイゼイスコア,数値評価スケール),および時間点 (3ヶ月と12ヶ月) に関するコンセンサスが達成されました.
主要な成果:
- 国際的なコンセンサスは,臨床的および放射線学的の治癒,再発,新しいの発達,合併症 (Clavien-Dindo),および再介入のための標準化された定義に達しました.
- 選択された器具には,アナルフィッスル生活の質スケール,ヴァイゼイスコア,および患者の満足度に関する数値評価スケールが含まれています.
- 結果評価のための標準化されたタイムポイントは,治療後3ヶ月と12ヶ月で確立されました.
結論:
- 開発されたAFCOMSは,暗号腺性門フィスチュラ研究のための標準化された定義と測定ツールを提供します.
- AFCOMSの実施により,研究における報告の一貫性が向上します.
- この標準化により,頭の研究における堅実なエビデンスの合成が容易になります.
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