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Updated: Feb 19, 2026

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches
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マキュラ: 網膜と主視系のためのマルチスケールシミュレーションプラットフォーム.

Bruno Cessac1, Erwan Demairy2, Jérôme Emonet1

  • 1Université Côte d'Azur, Biovision Team and Neuromod Institute, Inria, Sophia Antipolis, France.

Frontiers in neuroinformatics
|February 18, 2026
PubMed
まとめ

マキュラ (Macular) は,神経生物学者が,網膜と視覚系について,シリコで仮説を検証できるようにする新しいシミュレーションプラットフォームです. プログラミングを必要とせずにカスタマイズされた3Dモデルとシミュレーションを可能にします.

キーワード:
グラフィカルユーザーインターフェース (GUI)イン・シリコ・実験数値シミュレーションによる数値シミュレーション.主要視野系である視覚系.網膜 (レチナ) 網膜 (レチナ) 網膜 (レチナ) 網膜 (レチナ) 網膜 (レチナ) 網膜 (レチナ) 網膜 (レチナ) 網膜 (レチナ) 網膜 (レチナ) 網膜 (レチナ)

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Visual System01:26

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Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
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Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
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The retina is a layer of nervous tissue at the back of the eye that transduces light into neural signals. This process, called phototransduction, is carried out by rod and cone photoreceptor cells in the back of the retina.
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At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
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