関連する実験動画

Updated: Feb 19, 2026

Functional Characterization of RING-Type E3 Ubiquitin Ligases In Vitro and In Planta
10:27

Functional Characterization of RING-Type E3 Ubiquitin Ligases In Vitro and In Planta

Published on: December 5, 2019

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変異された基質特異性を持つ植物由来タンパク質リガスの合理的な設計

Yan Zhou1, Simon J de Veer1, Tristan J Tyler1

  • 1Institute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane QLD 4072, Australia.

Biochemistry
|February 18, 2026
PubMed
まとめ

研究者らは,重要なチロシン残基を改変することによって,タンパク質改変に不可欠なアスパラギニルリガゼを設計した. この改変により,タンパク質のラベル付けやサイクリングなどの多様な用途のために,それらの基板特異性を成功裏に拡張しました.

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