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Updated: Feb 20, 2026

Isolation and Analysis of Plasma Lipoproteins by Ultracentrifugation
06:47

Isolation and Analysis of Plasma Lipoproteins by Ultracentrifugation

Published on: January 28, 2021

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APOA5 c.553G>T関連高トリグリセリデミアのリバーシブルに低下したリポプロテインリパゼは,ペマフィブラートで治療に成功しました

Shozo Miyauchi1, Yuji Utsunomiya1, Masashi Okamoto1

  • 1Department of Diabetes and Endocrinology, Ehime Prefectural Central Hospital, Matsuyama, Ehime, Japan.

Endocrinology, diabetes & metabolism case reports
|February 18, 2026
PubMed
まとめ

希少な同同位体APOA5変異は,ライフスタイルの変化に反応しない重度の高トリグリセリデミアを引き起こしました. ペマフィブラート療法はトリグリセリドレベルを正常化し,リポタンパク質リパース機能を改善し,遺伝性高トリグリセリデミアの有効性を実証しました.

キーワード:
アポリポプロテイン A-Vハイパーキロミクロネミア症候群ハイパルトリグリセリデミアリポプロテインリペアゼ (lipoprotein lipase) とはペマフィブラート (Pemafibrate) とは

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