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Olfaction

Olfaction

The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...

Predicting Molecular Geometry

Predicting Molecular Geometry

VSEPR Theory for Determination of Electron Pair Geometries

Olfactory Receptors: Location and Structure

Olfactory Receptors: Location and Structure

The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...

Physiology of Smell and Olfactory Pathway

Physiology of Smell and Olfactory Pathway

Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...

Tactile and Chemical Senses

Tactile and Chemical Senses

Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex. This...

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関連する実験動画

Updated: Jun 9, 2026

Olfactory Context Dependent Memory: Direct Presentation of Odorants

Olfactory Context Dependent Memory: Direct Presentation of Odorants

Published on: September 18, 2018

Doty 2025への対応,構造からの匂いを予測することは有用です.

Robert Pellegrino¹, Emily J Mayhew², Joel D Mainland^1,3

¹Monell Chemical Senses Center, Philadelphia, Pennsylvania, 19104 United States.

Chemical senses

|February 18, 2026

まとめ

この研究は,匂いの空間を定量化するための進歩を強調し,歴史的見解に挑戦しています. 最近の物理化学モデリングの進歩は,嗅覚の予測ルールを提供し,以前の制限を超えています.

キーワード:

構造と匂いの関係化学感知知覚は,化学感知知覚である.歴史は歴史の歴史は歴史の歴史は歴史機械学習 (Machine Learning) とは,機械学習 (Machine Learning) とは,機械学習 (Machine Learning) と呼ばれるものです.匂いの混合物匂いの混合物心理物理学心理物理学とは

さらに関連する動画

Real-time In Vitro Monitoring of Odorant Receptor Activation by an Odorant in the Vapor Phase

Real-time In Vitro Monitoring of Odorant Receptor Activation by an Odorant in the Vapor Phase

Published on: April 23, 2019

Constructing an Olfactometer for Rodent Olfactory Behavior Studies

Constructing an Olfactometer for Rodent Olfactory Behavior Studies

Published on: April 11, 2025

関連する実験動画

Last Updated: Jun 9, 2026

Olfactory Context Dependent Memory: Direct Presentation of Odorants

Olfactory Context Dependent Memory: Direct Presentation of Odorants

Published on: September 18, 2018

Real-time In Vitro Monitoring of Odorant Receptor Activation by an Odorant in the Vapor Phase

Real-time In Vitro Monitoring of Odorant Receptor Activation by an Odorant in the Vapor Phase

Published on: April 23, 2019

Constructing an Olfactometer for Rodent Olfactory Behavior Studies

Constructing an Olfactometer for Rodent Olfactory Behavior Studies

Published on: April 11, 2025

科学分野:

嗅覚科学とは,嗅覚の科学である.
化学センセーションの研究
感覚的知覚感覚的知覚感覚的知覚

背景:

歴史的な匂いの分類レビューは,しばしば現代の進歩を無視します.
匂いの知覚は認知的要因の影響を受け,化学的特性への直接的なマッピングを複雑にします.
以前のモデルは,分子構造のみに基づいて匂いの質を予測するのに苦労しました.

研究の目的:

Doty (2025) による匂いの分類の歴史的レビューを評価する.
匂いの空間と物理化学モデルの定量化における最近の進歩を強調する.
歴史的レビューを現在の嗅覚研究のためのベースラインとして位置づけること.

主な方法:

文献レビューと既存の嗅覚研究の批判的分析.
歴史的な匂いの分類理論と現代の定量的な方法の比較.
嗅覚における物理化学的性質の予測力の評価.

主要な成果:

ドーティの歴史的レビューは,包括的ではあるが,匂いの領域における最近の定量的な進歩を過小評価している.
物理化学的性質は,匂いの質を予測する上でますます効果的です.
嗅覚科学は,純粋に認知的な説明を超えて,予測モデルに向かって動いています.

結論:

嗅覚科学の分野は,匂いの分類における歴史的制約を超越しています.
物理化学モデリングの進歩は,嗅覚の実践的かつ予測的なルールを提供しています.
Dotyのレビューは,匂いの研究の最終的なエンドポイントではなく,歴史的基盤として機能します.